氨溴索治疗轻中度早产儿呼吸窘迫综合征的疗效分析

目的：观察轻中度呼吸窘迫综合征早产儿应用氨溴索治疗的临床效果。方法取2012年7月-2013年4月本院收治60例新生儿肺透明膜病患儿并随机将其均分为对照组与实验组各30例，对照组接受经鼻持续气道正压通气（NCPAP）治疗，实验组在此基础上给予大剂量氨溴索治疗，观察两组住院天数、病情转归、呼吸指标及并发症情况。结果与对照组相比，实验组用氧时间更短、呼吸窘迫症状以及血气指标改善更明显、并发症发生率更低（P〈0.05）。结论在新生儿轻中度呼吸窘迫综合征治疗中，应用大剂量氨溴索可收到满意疗效，临床应予以推广应用。

Efficacy of mild to moderate respiratory distress syndrome in premature children ambroxol treatment

Objective To observe the clinical effect of mild to moderate respiratory distress syndrome in premature children ambroxol treatment. Methods 60 cases of hyaline membrane disease in children from July 2012 to April 2013 in our hospital were divided into the control group and experimental group, 30 cases in each group.The control group received nasal continuous positive airway pressure ventilation （NCPAP） treatment, the experimental group were given large doses of ambroxol treatment on the basis of the control group.Hospitalization, illness outcomes, indicators and respiratory complications of the two groups were observed. Results Compared with the control group, the experimental group had a shorter time with oxygen, respiratory distress and blood gas index improved more significantly, lower complication rates（P〈0.05）. Conclusions In neonates with mild to moderate respiratory distress syndrome therapy, high dose ambroxol receive satisfactory clinical use should be promoted.