绝经后女性良性阵发性位置眩晕患者血清钙离子、维生素D及骨转换代谢指标研究

目的 探讨绝经后女性良性阵发性位置性眩晕(BPPV)患者血清钙离子、维生素D以及骨转换代谢相关指标的关系.方法 选取2016年5月-2019年6月本院收治的绝经后BPPV患者180例为研究对象,依据骨密度分为正常骨密度组(47例)、骨密度减少组(54例)和骨质疏松组(79例),选择同期60例骨质疏松症(无眩晕)患者作为...

Study on serum calcium ion,vitamin D and bone conversion and metabolism in postmenopausal women with benign paroxysmal positional vertigo

Objective To investigate the relationship between serum calcium,vitamin D and bone turnover metabolism related indexes in postmenopausal women with benign paroxysmal positional vertigo(BPPV). Methods A total of 180 patients with postmenopausal BPPV treated in our hospital from May 2016 to June 2019 were selected as research subjects. They were divided into normal bone density group(47 cases),osteopenia group(54 cases) and osteoporosis group(79 cases) based on bone mineral density,and 60 cases of bone mass were selected during the same period. Patients with osteoporosis(no vertigo) were used as a control group,and retrospective analysis was performed on vitamin D,blood calcium ions and bone turnover metabolism related indexes between the groups. Results Vitamin D levels in the osteoporosis group were significantly lower than the other three groups,urinary deoxypyridoline(u-DPD) was significantly higher than the other three groups,and osteocalcin was significantly higher than the normal bone density group and the bone density reduction group,with the differences statistically significant(P < 0. 05). Multiple regression analysis showed that osteoporosis and serum vitamin D deficiency were risk factors for BPPV(OR = 2. 804,OR = 2. 003,P < 0. 05). Conclusion Osteoporosis,vitamin D deficiency,and bone turnover metabolites are related to postmenopausal BPPV,which should be highly valued in the clinic.