Hilson血流灌注指数在肾脏疾病中的应用

目的 探讨Hilson血流灌注指数(PI)在肾病患者中的临床应用价值。 方法 20例健康者为对照组, 80例肾脏疾病患者为疾病组, 测定两组的Hilson血流PI及肾小球滤过率(GFR)。 结果 对照组左肾PI为147.2±41.14, 右肾PI为155.25±41.73, 疾病组的慢性肾功能不全、肾动脉狭窄、肾病综合征、肾积水、输尿管结石及肾结石患者的左、右肾PI分别为459.28±68.15、476.67±38.99；436.14±61.88、420.85±66.39；379.40±111.00、372.20±99.52；333.75±140.94, 321.08±132.43；267.75±149.93、283.37±142.63。轻、中、重度肾功能受损患者的左、右肾PI分别为328.62±41.21、335.14±39.85；412.27±53.81、427.86±61.12；466.81±110.64、471.64±112.96, 均高于正常对照组, PI结果与GFR呈负相关, 相关系数r=-0.741。 结论 Hilson血流PI有较高的临床应用价值。

Application of Hilson perfusion index in kidney disease

Objective To investigate the clinical application value of Hilson perfusion index(PI) in patients with kidney disease. Methods The PI value and glomerular filtration rate(GFR) of 20 normal people and 80 patients with kidney disease were measured. Results The normal PI values for the left and right kidneys were 147.2±41.14 and 155.25±41.73, respectively, whereas the PI values for chronic renal failure, stenosis of renal artery, nephrotic syndrome, hydronephrosis, and renal calculus for the left and right kidneys were 459.28±68.15, 476.67±38.99; 436.14±61.88, 420.85±66.39; 379.40±111.00, 372.20±99.52; 333.75±140.94, 321.08±132.43; and 267.75±149.93, 283.37±142.63, respectively. Moreover, the PI values for mild, moderate, and severe renal impairment of the left and right kidneys were 328.62±41.21, 335.14±39.85; 412.27±53.81, 427.86±61.12; and 466.81±110.64, 471.64±112.96, respectively, which were higher than those in the normal control group. The PI results were negatively correlated with GFR, and the correlation coefficient(r) was 0.741. Conclusion Hilson perfusion index exhibited high clinical value.