Toxin profiles and resistances to macrolides and newer fluoroquinolones as epidemicity determinants of clinical isolates of Clostridium difficile from Warsaw, Poland |
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| Authors: | Pituch Hanna van Leeuwen Willem Maquelin Kees Wultańska Dorota Obuch-Woszczatyński Piotr Nurzyńska Grazyna Kato Haru Reijans Martin Meisel-Mikołajczyk Felicja Łuczak Mirosław van Belkum Alex |
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| Affiliation: | Department of Medical Microbiology, Medical University of Warsaw, Chalubinski Street, 02-004 Warsaw, Poland. hanna.pituch@ib.amwaw.edu.pl |
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| Abstract: | Amplified fragment length polymorphism genotypes, antibiotic resistance profiles, and toxin profiles of Clostridium difficile strains from Warsaw were determined. The isolates segregate in six major genotypes, coinciding with toxin profiles. Most of the toxin A-negative toxin B-positive toxin CDT-negative strains possess ermB, and several strains were resistant to fluoroquinolones. Resistograms and toxin types of C. difficile strains are epidemicity determinants. |
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