富血小板血浆治疗在腰痛的应用与研究进展

腰痛(LBP)是一种常见的临床症状，也是导致残疾和功能障碍的主要原因之一。在骨关节所致LBP的病因中以退行性病变占多数，其中椎间盘退变为主要诱因，还涉及腰椎小关节、骶髂关节、尾骨的病变等。LBP治疗方式从保守治疗过度到手术治疗，疼痛缓解为大多数患者的结局指标，然而并未起到结构修复的作用。鉴于富血小板血浆(PRP)疗法的再生修复潜力及在临床上的广泛应用，本文回顾了PRP与LBP有关的研究，旨在探索PRP治疗LBP的有效性与安全性及相关的参数指标，加速治疗进展。

Application and research progress of platelet-rich plasma therapy in low back pain

Low back pain (LBP) is a common clinical symptom and one of the leading causes of disability and dysfunction. Degenerative lesions account for the majority of the causes of LBP caused by bone and joint, among which intervertebral disc regression is the main trigger, and also involves the lesions of lumbar facet joints, sacroiliac joints, and coccyx. Treatment ranged from conservative to surgical, with pain relief as an outcome for most patients, but no structural repair. In view of the regenerative repair potential of platelet-rich plasma (PRP) therapy and its wide clinical application, this article reviews the research related to PRP and LBP, aiming to explore the efficacy and safety of PRP in the treatment of LBP and related parameter indicators, and accelerate the progress of treatment