A new subgenotype 2.1d isolates of classical swine fever virus in China, 2014 |
| |
| Affiliation: | 1. State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, China;2. China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Nanyang Normal University, Nanyang 473061, China;3. Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China;1. Animal and Plant Quarantine Agency (QIA), 175 Anayangro Manangu Anyangsi, Gyeonggido 430-824, South Korea;2. Department of Clinical Laboratory Science, Semyung University, Semyung-ro 65, Jecheon, Chungbuk 390-711, South Korea;3. Konkuk University, 1 Hawayangdong Gwangjingu, Seoul 143-701, South Korea;1. College of Life Science, Shandong Normal University, Jinan 250014, China;2. Department of Computer and Information Science, Fordham University, Bronx, NY 10458, USA |
| |
| Abstract: | The lapinized attenuated vaccine against classical swine fever (CSF) has been used in China for over half a century and has generally prevented large-scale outbreaks in recent years. However, since late 2014, a large number of new cases of CSF were detected in many immunized pig farms in China. Several of these CSV viruses were isolated and characterized. Phylogenetic and genomic sequence analyses indicate that these new isolates, as well as some reference isolates, form a new subgenotype named 2.1d, and share several consistent molecular characteristics. Since these new isolates emerged in disparate geographic regions within 5 months, this suggests that these isolates may be widespread. Given that current vaccines do not appear to provide effective protection against this new subgenotype, further investigation of these strains is urgently needed. |
| |
| Keywords: | Classical swine fever virus New subgenotype E2 |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
