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113例男性HIV-1抗体阳性吸毒者蛋白免疫印迹带型分析
引用本文:刘燕,严宇斌,曾健君,方巧云. 113例男性HIV-1抗体阳性吸毒者蛋白免疫印迹带型分析[J]. 中国热带医学, 2011, 11(11): 1330-1331
作者姓名:刘燕  严宇斌  曾健君  方巧云
作者单位:惠州市疾病预防控制中心,广东惠州,516003
摘    要:
目的分析HIV-1抗体阳性吸毒者的WB带型,了解惠州市男性吸毒人群WB带型的分布特征。方法对本实验室2007~2010年的HIV-1抗体确证检测阳性男性吸毒者的WB带型进行统计分析。结果 113份HIV-1抗体确证检测阳性男性吸毒者的WB带型中,gp160、gp120带型的出现率均在100%,p66、p51、gp41、p31、p24带型的出现率均在96%以上,p55,p17带型的出现率分别为71.68%和80.53%;WB全带型出现率为59.30%(67/113);不同年龄组带型差异无统计学意义。结论抗env和gag基因编码蛋白的抗体gp160、gp120、gp41、p24阳性率高,是确证HIV-1感染的必备条件;惠州市的HIV亚型、传播途径和WB带型之间的关系有待进一步的调查和研究。

关 键 词:HIV-1抗体  蛋白免疫印迹(WB)法  WB带型  男性  吸毒者

Analysis of Western blot band pattern of 113 male drug addicts positive for HIV-1 virus
LIU Yan,YAN Yu-bin,ZENG Jian-jun,et al.. Analysis of Western blot band pattern of 113 male drug addicts positive for HIV-1 virus[J]. China Tropical Medicine, 2011, 11(11): 1330-1331
Authors:LIU Yan  YAN Yu-bin  ZENG Jian-jun  et al.
Affiliation:LIU Yan,YAN Yu-bin,ZENG Jian-jun,et al.(Huizhou Municipal Centre for Disease Control and Prevention.Huizhou 516003,Guangdong P.R.China)
Abstract:
Objective To understand the distribution of western blot(WB) bands of male drug addicts infected with HIV-1 virus in Huizhou City.Methods All the HIV-1 antibody positive samples of drug addicts from 2007 to 2010 in our laboratory were collected and the WB bands were analyzed.Results Among the 113 samples,gp160,gp120 were expressed in 100% of the samples,p66,p51,gp41,p31,p24 band were expressed in over 96% of the samples;p55,p17 was expressed in 71.68% of the samples and 80.53% samples;the percentage of the ...
Keywords:HIV-1 antibody  Western blot test  WB band  Male drug addict  
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