抗菌药物临床应用回顾性调查

目的了解抗菌药物使用情况,为临床合理使用抗菌药物提供依据。方法回顾性调查本院老年患者2002年1~9月824份出院病历,统计抗菌药物使用率并分析各科抗菌药物使用情况。结果824份病历中,使用抗菌药物有405份占49.15%,共使用51种,其中使用率最高的5种为头孢哌酮/舒巴坦、青霉素、哌拉西林、诺氟沙星、阿莫西林,单独用药139例,占16.87%,二联用药328例,占39.81%,>二联用药357例,占43.33%,给药途径以静脉滴注为主,占给药途径>70%。结论全部用药基本合理,但预防性用药档次过高、时间过长,应加强抗菌药物使用的控制,严格掌握用药原则,为临床合理用药提供依据。

Clinical Application of Antibiotic: A Retrospective Survey

OBJECTIVE To know the rational use of antibiotic and give evidence to improve the application management on drug-using in hospital. METHODS Totally 824 cases of old age patients in Jan to Sep 2002 were investigated retrospectively,and the usage of antibiotic in different departments was analyzed. RESULTS In 824 cases reported,405 cases used antibiotic and accounted for 49.15%,From them 139 cases(16.89%) were for single-drug therapy,328 cases(39.81%) for dual-drug therapy,357 cases(43.33%) were for multidurg combination therapy.Intravenous drip was the major route of administration and accounted for more than 70%. CONCLUSIONS The use of antibiotic is rational on the whole,but the antibiotic used is not always necessary and the time for prevention is too long.It must control the application of antibiotic and grasp the principle of antibiotic usage and give evidence to improve the application management on drug-using in hospital.