Interleukin 2 (IL2) is assigned to human chromosome 4 |
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| Authors: | T. Shows R. Eddy L. Haley M. Byers M. Henry T. Fujita H. Matsui T. Taniguchi |
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| Affiliation: | (1) Department of Human Genetics, Roswell Park Memorial Institute, New York State Department of Health, 14263 Buffalo, New York;(2) Department of Biochemistry, Cancer Institute, Japanese Foundation for Cancer Research, Toshima-ku, 170 Tokyo, Japan |
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| Abstract: | ![]()
The human gene for interleukin 2 (IL2)was assigned to chromosome 4 using human-mouse somatic cell hybrids and Southern filter hybridization of cell hybrid DNA. To identify IL2,a recombinant DNA probe (pIL2-50A) was used which contained a human interleukin 2 cDNA insert which hybridized to a 3.5-kb fragment in human DNA when cleaved with the restriction enzyme EcoRL. |
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