Electrophysiological correlates of semantic processing during encoding of neutral and emotional pictures in patients with ADHD |
| |
| Authors: | Kerstin Krauel Emrah Duzel Hermann Hinrichs Daniel Lenz Christoph S. Herrmann Stephanie Santel Thomas Rellum Lioba Baving |
| |
| Affiliation: | 1. Department of Neurology and Center for Advanced Imaging, University of Magdeburg, Germany;2. Institute of Cognitive Neurology and Dementia Research, University of Magdeburg, Germany;3. Institute of Cognitive Neuroscience, University College London, United Kingdom;4. Department of Biological Psychology, University of Magdeburg, Germany;5. Department of Child and Adolescent Psychiatry, University of Magdeburg, Germany;6. Department of Child and Adolescent Psychiatry, Center for Integrative Psychiatry, University of Kiel, Germany;1. Bard College, Annandale-on-Hudson, NY, USA;2. Binghamton University, Binghamton, NY, USA;1. MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King''s College London, UK;2. Laval University and Institut Universitaire en Santé Mentale de Québec, Québec, Canada;3. Academic Centre for the Study of Behavioural Plasticity, Vita-Salute San Raffaele University, Milan, Italy;4. Child and Adolescent Psychiatry, Institute of Psychiatry, King''s College London, UK;5. Swartz Center for Computational Neuroscience, Institute for Neural Computation, University of California San Diego, USA;1. University of Durham, UK;2. Nanyang Technological University, Singapore;3. University of Brasília, Brazil;4. Monash University, Malaysia |
| |
| Abstract: | ![]()
The current study investigated the relevance of semantic processing and stimulus salience for memory performance in young ADHD patients and healthy control participants. 18 male ADHD patients and 15 healthy control children and adolescents participated in an ERP study during a visual memory paradigm with two different encoding tasks requiring either perceptual or semantic processing of neutral and emotional pictures. ADHD patients and healthy controls both showed a more negative slow-wave in response to task cues signalling semantic as compared to perceptual stimulus processing. In contrast to ADHD patients, healthy control children showed a larger increase in memory performance for deeply processed neutral pictures which was accompanied by a more positive mid-latency ERP component (so-called P300) after stimulus onset. Our results demonstrate that ADHD patients succeeded in allocating neural resources in preparation of different task demands. However, this increase in preparatory activation to the semantic task cue did not suffice to support successful processing and encoding of neutral stimuli to the same extent as in healthy controls. These findings provide evidence that ADHD patients show deficits in translating pre-stimulus mobilization of neural resources to successful memory formation in the absence of salient stimulus material. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
