拉萨190例甲型H1N1流感的流行病学特点及临床分析

目的 探讨2009年拉萨甲型H1N1流感的流行病学特征及临床特点.方法 对2009年9-12月我院收治的190例甲型H1N1流感确诊病例的流行病学、临床表现及实验室检查等资料进行回顾性分析.结果本次拉萨地区暴发的甲型H1N1流感主要发生在秋冬季,9、10月为高峰.190例病例中,男性106例(55.79%),女性84例(44.21%),患者的平均年龄(16.66±9.78)岁,以7～17岁为主,学生139例(73.16%),藏族144例(75.79%).临床表现以发热、咳嗽、咽痛、咽充血和扁桃体肿大为主,172例有发热(90.53%).所有病例均未接种过甲型H1N1流感疫苗,入院时甲型H1N1流感病毒核酸检测均为阳性,176例(92.63%)病毒快速检测阳性.174例(91.58%)使用利巴韦林等抗病毒治疗取得较好疗效,184例痊愈出院,无死亡病例.结论 本组患者均为易感人群,因此流行期间接种甲型流感疫苗,提高人群免疫力势在必行.

Analysis on the epidemiological and clinical characteristics of 190 cases with A(H1N1)influenza in Lhasa

Objective To investigate the epidemiological and clinical features of 190 A(H1N1)influenza cases in 2009 Lhasa.Methods 1he clinical data of 190 hospitalized cases with A(H1N1)influenza in our hospital from September to December 2009 were collected and retrospectively analyzed in epidemiology,clinical features and laboratory test.Results This outbreak of A(H1N1)influenza in Lhasa occurred during autumn and winter with the peak period in September and October.Of the 190 cases,there were 106(55.79%)males,84(44.21%)females.The average age was(16.66±9.78)years old,most of the cases were 7-17 years old.139(73.16%)cases were students.144(75.79%)cases were Tibetan people.The main clinical manifestations were fever,cough,pharyngalgia,pharyngitis,tonsillitis,and172(90.53%)cases had fever.No vaccination was implemented in all the patients before,all of them were positive for the A(H1N1)influenza virus nucleic acid testing on admission,176(92.63%)cases were positive for rapid detection of A influenza virus,174(91.58%)cases accepted ribavirin and other anti-viral therapy to achieve better effect.184 cases were recovery,and there were no death cases.Conclusions The patients in this group are non-immune population,so it is imperative to vaccinate people during influenza pandemic.