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Fetal programming of the metabolic syndrome |
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| Authors: | Aleksandra Marciniak Jolanta Patro-Małysza Żaneta Kimber-Trojnar Beata Marciniak Jan Oleszczuk Bożena Leszczyńska-Gorzelak |
| Affiliation: | Department of Obstetrics and Perinatology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland |
| Abstract: | Prenatal development is currently recognized as a critical period in the etiology of human diseases. This is particularly so when an unfavorable environment interacts with a genetic predisposition. The fetal programming concept suggests that maternal nutritional imbalance and metabolic disturbances may have a persistent and intergenerational effect on the health of offspring and on the risk of diseases such as obesity, diabetes, and cardiovascular diseases. |
| Keywords: | fetal development genetic predisposition to disease metabolic syndrome X nutritional status pregnancy |
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