| Affiliation: | 1. Université Paris Descartes EA 3620, Paris, France;2. AP‐HP, Service de Médecine Interne et Maladies Infectieuses, H?pital Bicêtre, Le Kremlin‐Bicêtre, France;3. AP‐HP, Laboratoire de Virologie, CHU Necker‐Enfants Malades, Paris, France;4. INSERM, U822, Le Kremlin‐Bicêtre, Université Paris‐Sud, Faculté de Médecine Paris‐Sud, AP‐HP, Le Kremlin‐Bicêtre, France;5. AP‐HP, Laboratoire de Virologie, Groupe Hospitalier Bichat‐Claude Bernard, Paris, France;6. Université Paris Diderot EA 4409, Paris, France;7. Laboratoire de Virologie, CHU de Caen, Caen, France;8. AP‐HP, Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Bichat‐Claude Bernard, Paris, France |
| Abstract: | Diagnosis of primary HIV‐1 infection is challenging due to the presence of a serological window; thus, HIV‐1‐RNA quantitation and/or measurement of p24 antigenemia are recommended in such cases. A patient was diagnosed at the time of primary HIV‐1 infection, he harbored a CFR02_AG subtype virus; quantitation of plasma HIV‐1‐RNA yielded an undetectable result according to one commercial assay, while HIV‐1‐RNA was detectable when measured with three other assays. J. Med. Virol. 82:1816–1818, 2010. © 2010 Wiley‐Liss, Inc. |
