0.75%罗哌卡因20mL与0.50%罗哌卡因30mL应用于超声引导下肌间沟臂丛阻滞的药效比较

目的 比较0.75%罗哌卡因20 mL与0.50%罗哌卡因30 mL应用于超声引导下肌间沟臂丛神经阻滞的效果.方法 44例美国麻醉医师学会(ASA)分级Ⅰ～Ⅱ级上肢手术患者,按随机双盲方法分成两组,在超声引导下行肌间沟臂丛阻滞.A组予0.50%罗哌卡因30 mL,B组予0.75%罗哌卡因20 mL.记录并比较两组患者麻醉前及麻醉后30 min内生命体征,感觉阻滞和运动阻滞情况、镇痛持续时间及不良反应.结果 两组患者麻醉效果均满意,均未发生心血管及中枢神经系统不良反应.两组间桡神经、正中神经和尺神经的感觉及运动阻滞起效时间、30 min内各神经完全阻滞率的差异均无统计学意义(P值均＞0.05).而A组的平均镇痛持续时间为(567.9±196.5)min,长于B组的(451.7±139.5)min,但差异无统计学意义(P＞0.05).结论 超声引导下肌间沟臂丛阻滞使用0.75%罗哌卡因20 mL与0.50%罗哌卡因30 mL在感觉阻滞和运动阻滞上具有相似的麻醉效果,但使用0.50%罗哌卡因30 mL可以延长镇痛时间,并可能降低发生不良反应的风险,因此更适用于肌间沟臂丛神经阻滞.

Pharmacodynamic comparison of ultrasound-guided interscalene brachial plexus block with 0.75% ropivacaine 20 mL versus 0.50% ropivacaine 30 mL

Objective To compare the pharmacodynamic effects of ultrasound-guided interscalene brachial plexus block by 0.75% ropivacaine 20 mL and 0.50% ropivacaine 30 mL.Methods Forty-four patients scheduled for elective upper limb surgery were randomly assigned to receive ultrasound-guided interscalene brachial plexus block with 0.50% ropivacaine 30 mL(n=22,group A)or 0.75% ropivacaine 20 mL(n=22,group B).A constant dose of ropivacaine was administered to all patients.Sensory and motor block in the upper limb and co...