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| 天麻对D-半乳糖所致衰老小鼠的改善作用 | |
| 引用本文： | 高南南,于澍仁,刘睿红,徐锦堂. 天麻对D-半乳糖所致衰老小鼠的改善作用[J]. 中草药, 1994, 25(10): 521-523 |
| 作者姓名： | 高南南 于澍仁 刘睿红 徐锦堂 |
| 作者单位： | 中国医学科学院药用植物资源开发研究所!北京100094 |
| 摘 要： | 小鼠球后注射D－半乳糖80mg／kg，50d后造成亚急性衰老模型，同时口服天麻4、8g／kg能显著恢复D－半乳糖衰老模型小鼠被动回避反应能力的下降，明显提高RBC中SOD活力，皮肤羟脯氨酸含量，减少心肌脂褐质，对脑、肝脂褐质减少不明显。 |
| 关 键 词： | 天麻 衰老 半乳糖 脂褐质 超氧化物歧化酶 |
| 收稿时间： | 1993-09-23 |
Beneficial Effect of Gastrodia on Some Aging Disorders Induced by D-Galactose in Mice |
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| Gao Nannan,Yu Shuren,Liu Ruihong and Xu Jintang. Beneficial Effect of Gastrodia on Some Aging Disorders Induced by D-Galactose in Mice[J]. Chinese Traditional and Herbal Drugs, 1994, 25(10): 521-523 | |
| Authors: | Gao Nannan Yu Shuren Liu Ruihong Xu Jintang |
| Affiliation: | Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing |
| Abstract: | A model of s bacute senility state was established in mice by successive retrobulbar injectiou of 80 mg/kg D-galactose for 50 days. Concomitant oral administration of 4 g/kg and 8 g/kg gastrodia can effectively recovcr the decreased ability of the passive avoid ance reaction in the model animals.The activity of RBC SOD and the contents of hydroxyproline in the animals skin were markedly increased as well as the lipofuscin of myocardium. However, gastrodia was less effective to lower lipofuscin in liver and brain. |
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