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The electrorectogram in Hirschsprung's disease
Authors:Ahmed Shafik
Affiliation:(1) Department of Surgery Research, and Faculty of Medicine, Cairo University, Cairo, Egypt;(2) 2 Talaat Harb Street, Cairo, Egypt
Abstract:The electrorectographic pattern of Hirschsprung's disease (HD) was studied in 14 HD patients with a mean age of 4.6 ± 1.5 years; 7 healthy children acted as controls. Monpolar recordings were made from a silver-silver chloride electrode situated 1 cm from the tip of a 4 F catheter attached to the rectal mucosa by suction. At least four 120-min recording sessions were performed for each subject. No complications were encountered. Regular and reproducible triphasic pacesetter potentials (PP) were recorded from all healthy children, followed randomly by bursts of action potentials (AP). No PP or AP were recorded from patients with HD; the ldquosilentrdquo electrorectogram (ERG) was reproducible. Since numerous difficulties in histopathologic interpretation affect the reliability of rectal biopsy for the diagnosis of HD, the ERG may play a role in this respect. The ERG is noninvasive and nonradiologic; however, until this investigati tool is substantiated by the work of other investigators, a histologic diagnosis needs to be made before undertaking a pull-through procedure.
Keywords:Hirschsprung's disease  Megacolon  Rectum  Aganglionosis  Electrorectogram
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