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Expression of c-fos, fos B, and egr-1 in the medial preoptic area and bed nucleus of the stria terminalis during maternal behavior in rats
Authors:Michael Numan   Marilyn J Numan  Sandra R Marzella  Andrea Palumbo
Affiliation:Department of Psychology, Boston College, Chestnut Hill, MA 02167, USA
Abstract:The spatial and temporal pattern of expression of the protein products of immediate early genes (IEGs) c-fos, fos B, and egr-1 were mapped in medial preoptic area (MPOA) and ventral bed nucleus of stria terminalis (VBST) during maternal behavior in rats. Immunocytochemical analysis indicated significant increases in the number of cells expressing c-Fos after 2 h of pup exposure, while Fos B levels showed a delayed response, reaching maximal levels after 6 h.
Keywords:Maternal behavior   Medial preoptic area   Immediate early gene   c-Fos   Fos B
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