| HAART对AIDS患者中短期效果的Meta分析 |
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| 引用本文： | 赵玉遂,荆波,刘少楠,傅继华. HAART对AIDS患者中短期效果的Meta分析[J]. 中国艾滋病性病, 2012, 0(2): 79-81,106 |
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| 作者姓名： | 赵玉遂 荆波 刘少楠 傅继华 |
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| 作者单位： | 山东省医学科学院基础医学研究所;滨州职业学院护理学院;威海市疾病预防控制中心;山东省疾病预防控制中心 |
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| 摘 要： | 目的综合评价国内接受高效抗反转录病毒治疗(HAART)的艾滋病(AIDS)病人的CD4+T细胞数量、病毒载量的中短期变化规律。方法全面检索相关文献,并按照事先定义的纳入和排除标准剔除不符合要求的文献,对纳入文献采用Meta分析方法进行综合定量分析。结果 AIDS病人HAART后3、6、12、18、24个月,CD4+T细胞数量平均分别增加了112.186个/μL、6.917个/μL、32.081个/μL、36.654个/μL、41.431个/μL;病毒载量平均log下降了2.475拷贝/mL、0.893拷贝/mL、0.140拷贝/mL。结论接受HAART的AIDS病人,中短期能够取得良好的治疗效果。
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| 关 键 词： | 艾滋病病人 高效抗反转录病毒治疗 中短期效果 Meta分析 |
Meta-analysis of effect of AIDS patients on HAART in the short-term |
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| Affiliation: | ZHAO Yu-sui,JING Bo,LIU Shao-nan,et al.(Institute of Medical Sciences,Jinan,Shandong 250062,China) |
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| Abstract: | Objective Evaluation of domestic AIDS patients receiving HAART CD+4T cell count,viral load in the short-term variation.Method The included studies acquired complying with comprehensive literature search methods and re-defined inclusion and exclusive criteria were analyzed by comprehensive quantitative meta-analysis.Results In patients with AIDS,after 3,6,12,18,24 months of receiving HAART,CD+4T cells increased by an average of 112.186/μL,6.917/μL,32.081/μL,36.654/μL,41.431/μL;viral load fell by an average 2.475log copy/mL,0.893 log copy/mL,0.140 log copy/mL.Conclusion The short-term HAART in AIDS patients can achieve good treatment results. |
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| Keywords: | AIDS patients HAART Short-term variation meta-analysis |
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