| 人参皂甙对大鼠离体主动脉活动的影响 |
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| 引用本文： | 王蓓蓓,郑肖钊.人参皂甙对大鼠离体主动脉活动的影响[J].基础医学与临床,1989(4). |
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| 作者姓名： | 王蓓蓓 郑肖钊 |
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| 作者单位： | 中日友好医院临床医学研究所生理室
(王蓓蓓)，中日友好医院临床医学研究所生理室(郑肖钊) |
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| 摘 要： | 在一定GS浓度下对大鼠离体主动脉存在双向性作用。正常状态下使其收缩,而在NA收缩的基础上则引起其舒张。 GS对大鼠离体主动脉活动影响的作用途径及其机制目前尚不清楚,其收缩和舒张均与胰岛素的效应相似,由此提示可能是类胰岛素样的作用。GS的舒张效应可能不需动脉壁内膜参与,而GS收缩效应可被阿托品所阻断,可能与平滑肌上胆碱能M受体激活有关。
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| 关 键 词： | 人参皂甙 离体大鼠主动脉条 胰岛素 |
Effect of Ginseng Saponins on Isolated Rat Aorta |
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| Wang Peipei Zheng Xiaozhao.Effect of Ginseng Saponins on Isolated Rat Aorta[J].Basic Medical Sciences and Clinics,1989(4). |
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| Authors: | Wang Peipei Zheng Xiaozhao |
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| Abstract: | This artical is designed to detect the effect of Ginseng Saponins (GS) on helixal aortic strips of rats. GS was extracted from Panax Ginseng. It can induce biphasic actions on isolated rat aorta. Under the normal condition it produces contractive response. Under the NA-induced contraction condition it produces dilative response. Insuline has the similar effect. It suggests that the contractive response of GS is in relation to marcarinic receptor. |
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| Keywords: | Ginseng Saponins (GS) Isolated rat aorta Insuline |
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