| 脉络宁注射液对麻醉犬血流动力学的影响 |
| |
| 引用本文： | 王兴旺,卞家驹,方泰惠,徐立,许立,袁冬萍,龙军,张松. 脉络宁注射液对麻醉犬血流动力学的影响[J]. 中国天然药物, 2003, 1(2): 107-110 |
| |
| 作者姓名： | 王兴旺 卞家驹 方泰惠 徐立 许立 袁冬萍 龙军 张松 |
| |
| 作者单位： | 1. 金陵药业股份有限公司技术中心,南京,210009
2. 南京中医药大学药理教研室,南京,210029 |
| |
| 基金项目： | 国家“十五”重大科技专项“创新药物和中药现代化”项目基金资助 (No .2 0 0 2AA2Z3 2 19)~~ |
| |
| 摘 要： | 目的：观察脉络宁注射液对麻醉犬血流动力学的影响。方法：采用麻醉犬在体心脏实验法。结果：脉络宁注射液能降低麻醉犬总外周血管阻力和左室舒张末期压,增加冠状动脉血流量,缩短左室射血时间,降低心肌总耗氧指数。结论：脉络宁注射液能改善麻醉犬血流动力学,这可能是其治疗心绞痛的药理学基础之一。
|
| 关 键 词： | 脉络宁注射液 麻醉 犬 血流动力学 影响 心绞痛 |
| 文章编号： | 1672-3651(2003)02-0107-04 |
| 修稿时间： | 2003-02-16 |
Effect of Mailuoning Injection on Hemodynamics in Anesthetic Dogs |
| |
| WANG Xing Wang ,BIAN Jia Ju ,FANG Tai Hui ,XU Li ,XU Li ,YUAN Dong Ping ,RONG Jun ,ZHANG Shong Technical Center,Jinling Pharmaceutical Company Limited,Nanjing. Effect of Mailuoning Injection on Hemodynamics in Anesthetic Dogs[J]. Chinese JOurnal of Natural Medicines, 2003, 1(2): 107-110 |
| |
| Authors: | WANG Xing Wang BIAN Jia Ju FANG Tai Hui XU Li XU Li YUAN Dong Ping RONG Jun ZHANG Shong Technical Center Jinling Pharmaceutical Company Limited Nanjing |
| |
| Affiliation: | WANG Xing Wang 1,BIAN Jia Ju 1,FANG Tai Hui 2,XU Li 2,XU Li 2,YUAN Dong Ping 2,RONG Jun 2,ZHANG Shong 2 1Technical Center,Jinling Pharmaceutical Company Limited,Nanjing 210009, 2 Department of Pharmacology,Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China |
| |
| Abstract: | AIM:To observe the effect of Mailuoning injection on hemodynamics in anesthetic dogs. METHOD:To employ the experimental technology of in situ heart of dogs. RESULT:The drug could decrease total peripheral vessel resistance and left ventricle end diastolic pressure,increase blood flow,shorten the blood shooting time of left ventricle,decrease the total oxygen consuming index in anesthetic dogs. CONCLUSION:Mailuoning injection can improve the hemodynamics in anesthetic dogs,which may be one of the pharmacological principles in the treatment of angina pectoris by the drug. |
| |
| Keywords: | Mailuoning injection Hemodynamics Angina pectoris In situ heart experiments in dogs |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
