EEG frequency content related to regional blood flow of cerebral cortex in cat

Summary The EEG frequency content in cats, anaesthetized by Nembutal and artificially ventilated, was altered by means of injections of either additional Nembutal or of Metrazol. The EEG in cerveau isolé preparations was also changed in the same way. The regional cortical blood flow was determined by means of the ⁸⁵Krypton technique. A high correlation was found between the frequency content of the EEG, measured by means of manual frequency analysis, and the regional cortical blood flow. The cortical blood flow increased when the mean frequency increased, and vice versa. A similar correlation was found when the EEG mean frequency was changed by means of sensory stimulation.On leave of absence from the University of Montpellier, France.This investigation was sponsored by the Swedish Medical Research Council (Project 21x-84-01 and 21x-84-02) and by the Wallenberg Foundation, Stockholm.