彩色多普勒超声评价乳腺癌新辅助化疗疗效的临床价值

目的:探讨彩色多普勒超声在评价乳腺癌新辅助化疗疗效上的临床价值?方法:应用彩色多普勒超声对65例乳腺癌患者接受乳腺癌新辅助化疗前后的乳腺癌病灶的超声指标改变进行观察,对化疗有效与化疗无效乳腺癌在新辅助化疗前后病灶内血流分级?最高流速(Vmax)及阻力指数(RI)值的变化进行观察?总结与新辅助化疗疗效相关的声像图指标以及血流指标?结果:彩色多普勒超声显示乳腺癌新辅助化疗后原发灶肿瘤大小显著缩小,形态变的不规则,边界多清晰可见,周边声带可消失,后方回声倾向正常?血流指标,在部分缓解患者中,新辅助化疗前后病灶内血流分级?最高流速及RI值变化均具有显著性差异;而在无变化 + 部分缓解患者中,新辅助化疗前后病灶内血流分级?最高流速及RI值变化均不具有显著性差异?结论:彩色多普勒超声在乳腺癌新辅助化疗疗效评价上具有较高的临床价值?

The clinical value of color doppler ultrasound in the evaluation of effect of the neoadjuvant chemotherapy in patients with primary breast cancer

Objective:To investigate the clinical value of color doppler ultrasound in evaluation of the effect of neoadjuvant chemotherapy for breast cancer. Methods:Total 65 patients with breast cancers before and after neoadjuvant therapy were examined with color doppler ultrasound. The index of ultrasound was observed,the degree of blood flow and hemodynamics index of the tumor were observed. Results:After neoadjuvant chemotherapy,there were significant differences in decrease of tumor size,volume,morphology irregularity,existence of surrounding halo,distinct boundary,increasing of internal echoes and rear echo. At the same time,the degree of blood flow and hemodynamics index of the tumor were decreased. Conclusion:Color doppler ultrasound provides an effective method in the evaluation of the effect of neoadjuvant chemotherapy in patients with primary breast cancer.