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有机锗与鲨肝醇对苯中毒小鼠升白细胞作用的比较研究
引用本文:张强,张凯,林立.有机锗与鲨肝醇对苯中毒小鼠升白细胞作用的比较研究[J].中国公共卫生,2000,16(5):419-420.
作者姓名:张强  张凯  林立
作者单位:济宁医学院职业卫生与环境医学研究所,272013
摘    要:评价有机锗(Ge-132)对苯中毒小鼠白细胞降低的治疗作用在制备动物模型的基础上,将符合诊断标准的动物给予鲨肝醇和不同剂量有机锗治疗。4周后,对其外周白细胞总数、分类、血红蛋白骨髓及脏器系数进行检测。结果显示:Ge-132对人工诱导苯中毒所致的外周白细胞降低有一定的治疗作用,它优于鳖肝醇,以500mg/kg剂量组治疗效果最佳。提示有机锗治疗苯中毒所致的白细胞减少症比鲨肝醇更有效,

关 键 词:Ge-132  鲨肝醇  苯中毒  有机锗  白细胞减少  治疗
修稿时间:1999年7月12日

Compared Study of Treatmental Effects of Ge- 132 and Bariolum on Decrease of WBC Counts in Bezene - Exposed Mice
Zhang Qiang.Compared Study of Treatmental Effects of Ge- 132 and Bariolum on Decrease of WBC Counts in Bezene - Exposed Mice[J].Chinese Journal of Public Health,2000,16(5):419-420.
Authors:Zhang Qiang
Abstract:To evaluate reatmental effects of Ge-132 and Batiolum on decrease of WBC counts in bezene-exposedmice.The mice conforming to diagnotic carteria were treated by Ge-132 and Batiolum indifferent dosdage.under the base of animal model.The peripheral WBC counts,WBC classification,heatoglobin level,bone marrow cell and dorgan coefficient were checked after four weeksd.Ge-132 has hematopoiesis effect in bezene-exposed mice and is better than Bdatiolum espeilly in 500mg/kg group.Ge-132 is better than Batiolum in treating decrease of WBC in bezene-exposed mice.
Keywords:Ge-132\ Batiolum\ Bezene-exposed
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