Successful control of pancreatic cancer pain using S-1 chemotherapy--a case report

A 59-year-old man had received chemotherapy with gemcitabine for nonresectable pancreatic cancer. After 14 months, he was hospitalized for obstructive jaundice and severe pain. Cholangioduodenostomy was performed, and the dose of opioids was increased. Although jaundice improved, the uncontrollable pain persisted. Chemotherapy with S-1 was initiated, and a dramatic improvement in the pain was observed. Consequently, the patient could be discharged from the hospital.