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Resistance to inhibitors of the human immunodeficiency virus type 1 integration |
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| Authors: | Daria J. Hazuda |
| Affiliation: | PhD. Biochemistry, State University of New York. Vice President, Worldwide Discovery Franchise |
| Abstract: | This review will summarize the role of integrase in HIV-1 infection, the mechanism of integrase inhibitors and resistance with an emphasis on raltegravir (RAL), the first integrase inhibitor licensed to treat HIV-1 infection. |
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