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The Pregnancy Depression Scale (PDS): a screening tool for depression in pregnancy
Authors:Lori L. Altshuler  Lee S. Cohen  Allison F. Vitonis  Stephen V. Faraone  Bernard L. Harlow  Rita Suri  Richard Frieder  Zachary N. Stowe
Affiliation:(1) Mood Disorders Research Program, Department of Psychiatry and Biobehavioral Sciences, University of California, 300 UCLA Medical Plaza, Suite 1544, P.O. Box 957057, Los Angeles, CA 90095-7057, USA;(2) Perinatal and Reproductive Psychiatry Clinical Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA;(3) Obstetrics and Gynecology Epidemiology Center, Brigham and Women’s Hospital, Boston, MA, USA;(4) Department of Psychiatry and Neuroscience, Upstate Medical University, State University of New York Upstate Medical University, Syracuse, NY, USA;(5) Department of Physiology, Upstate Medical University, State University of New York Upstate Medical University, Syracuse, NY, USA;(6) Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA;(7) Department of Obstetrics and Gynecology, Department of Family Medicine, University of California, Los Angeles, CA, USA;(8) Women’s Mental Health Program, Department of Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, GA, USA
Abstract:
Depression in pregnancy can be underdiagnosed as a consequence of the symptoms being misattributed to “normal pregnancy.” There are currently no validated clinician-rated scales that assess for depression specifically during pregnancy. We sought to develop a brief, convenient screening tool to identify depression in pregnant women in the community setting. Prospective mood data using the 28-item Hamilton Depression Rating Scale (HDRS) were collected monthly in 196 pregnant women with a history of a major depressive disorder. These data were analyzed to delineate those HDRS items associated (elevated) with normal pregnancy vs. those indicative of a pregnant woman meeting diagnostic criteria for a major depressive episode. Endorsement of symptoms on seven items of the HDRS were highly predictive of having a major depressive episode during pregnancy. We present a well-validated, brief scale to screen pregnant women for clinical depression. Whether this study will generalize to women who do not have a history of major depression remains to be studied.
Keywords:Pregnancy  Depression  Screening  Rating scale
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