多灶性脉络膜炎的眼底分析

目的 探讨多灶性脉络膜炎（MC）的临床特征，指导临床诊断及治疗。 方法 回顾性分析经眼底检查、荧光素眼底血管造影(FFA)或FFA和吲哚青绿血管造影（ICGA)确诊为MC18例患者的临床资料。结果18例患者28只眼眼底均表现为散在的黄白色或者灰黄色圆形或椭圆型病灶（双眼10例，单眼8例）；活动性病灶9只眼，非活动性病灶19只眼；7例患者7只眼伴有黄斑部脉络膜新生血管膜（CNV)。FFA显示病灶区早期呈弱荧光，后期荧光渗漏或荧光染色及透见荧光。 结论 MC由于少见，易误诊为其他疾病，FFA有助于确诊，并可指导治疗及判断视力预后。 (中华眼底病杂志, 2005, 21: 367-370)

Clinical observation of multifocal choroiditis

Objective To investigate the clinical features of multifocal choroiditis (MC) and guide the diagnosis and treatment. Methods Retrospective analysis of clinical data of 18 MC cases (28 eyes) who were diagnosed through fluorescein angiography (FFA) or indocyanine green angiography (ICGA) and fundus characteristics. Results Multiple round to oval lesions scattered throughout the posterior pole and peripheral areas of ocular fundi of all of the 28 eyes(binocular in 10 and monocular in 8) were found. Active focal lesions of ocular fundi were seen in 8 patients and inactive lesions in 10 patients. active and 10 cases were inactive. Choroidal neovascularization(CNV) in macular area was found in 7 patients. The images of FFA of the legions showed hypofluorescence in the early phase, with late leakage and gradual staining or window is defect in the late phase. Conclusions MC is a rare disease and often misdiagnosed to other disease and FFA helpful in diagnosis.