丛状纤维组织细胞瘤3例临床病理观察

目的 探讨丛状纤维组织细胞瘤临床病理特点及鉴别诊断要点.方法 对3例丛状纤维组织细胞瘤进行临床资料及光镜和免疫组化标记观察.结果 组织学特点:纤维结缔组织把肿瘤细胞分隔成丛状或结节状.结节则由单核或多核组织细胞样细胞构成,结节外周围绕短梭形的纤维母/肌纤维母细胞样细胞.部分结节则主要由纤维母细胞样细胞组成,不见多核巨细胞.免疫组化染色显示:单核或多核组织细胞样细胞表达CD68、α-ACT和溶菌酶,梭形细胞表达Vim和SMA.结论 丛状纤维组织细胞瘤是一种低度恶性的软组织肿瘤,其诊断主要依靠组织病理学和免疫组化标记.

Clinicopathologic observation of plexform fibrohistiocytic tumor of three cases

Purpose To study the clinical pathologic characteristics and differential diagnosis of plexform fibrohistiocytic tumor(PFT).Methods Three cases of PFT were studied by clinical data analysis,light microscopy and immunohistochemistry.Results The tumor cells were separated into plexiform or nodules by fibrous connective tissue,some of which were consisted of mononuclear histiocytoid cells and multinuclear giant cells in the center and there were fibroblast-like or myofibroblast-like cells at the periphery.The ...