| 大肠癌患者血清一氧化氮含量变化及其临床意义 |
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| 引用本文： | 施根林,何海明,刘金波,王新元. 大肠癌患者血清一氧化氮含量变化及其临床意义[J]. 临床军医杂志, 2000, 28(3): 15-16 |
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| 作者姓名： | 施根林 何海明 刘金波 王新元 |
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| 作者单位： | 武警江苏总队医院检验科,江苏,杨州,225003 |
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| 摘 要： | 目的 探讨大肠癌患者血清一氧化氮 (NO)含量变化的意义。方法 采用改进Griess法测定 2 5例大肠癌患者及 2 9例正常对照组血清NO含量。结果 大肠癌患者血清NO含量明显高于对照组 (P <0 .0 1) ,并与肿瘤的大小、浸润、淋巴结转移、分化程度及临床分期明显相关 (P <0 .0 1)。结论 大肠癌患者血清NO含量变化与肿瘤的浸润及转移等病理特征密切相关 ,测定血清NO含量对大肠癌患者的病情及预后判断有一定的参考价值。
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| 关 键 词： | 大肠肿瘤 一氧化氮 |
| 文章编号： | 1007-1725(2000)03-0015-02 |
| 修稿时间： | 2000-02-28 |
Changes in Serum Nitric Oxide in Patients with Colorectal Cancer and its Clinical Significance |
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| SHI Gen-lin,HE Hai-min,LIU Jin-bo,WANG Xin-yuan. Changes in Serum Nitric Oxide in Patients with Colorectal Cancer and its Clinical Significance[J]. Clinical Journal of Medical Officer, 2000, 28(3): 15-16 |
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| Authors: | SHI Gen-lin HE Hai-min LIU Jin-bo WANG Xin-yuan |
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| Abstract: | Objective To investigate the level changes of serum nitric oxide (NO) in patients with colorectal cancer and its significance Method Serum levels of NO in 25 patients with colorectal cancer and 29 healthy controls were measured by improved Griess assay Result The levels of serum NO were significantly higher in patients with colorectal cancer than that in control group ( P <0.01) The levels of NO were closely correlated with the tumour size and invasion and lyonph-node metastasis and histologic grade and clinical stage ( P <0.01) Conclusion The levels of serum NO are closely related to the tumour invasion and metastases, and the assay of serum NO may be useful in diagnosis and prediction of prognosis of colorectal cancer |
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| Keywords: | colorectal tumor nitric oxide |
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