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| 多普勒超声心动图评价吸入一氧化氮对闭塞性肺动脉高压的疗效 | |
| 引用本文： | 何建国,赵一举,程显声,刘汉英. 多普勒超声心动图评价吸入一氧化氮对闭塞性肺动脉高压的疗效[J]. 中国循环杂志, 1995, 0(12) |
| 作者姓名： | 何建国 赵一举 程显声 刘汉英 |
| 作者单位： | 中国医学科学院，中国协和医科大学心血管病研究所，中国协和医科大学阜外心血管病医院 |
| 摘 要： | 本文报道了应用多普勒超声技术评价吸入一氧化氮（ＮＯ）对１５例闭塞性肺动脉高压患者的疗效。结果表明，吸入ＮＯ后收缩期跨三尖瓣峰值压差平均降低２２．５％（Ｐ＜０．００１），提示肺动脉高压和右心室阻力负荷显著减轻。左心室舒张末期容积平均增加１２．６％（Ｐ＜０．０５），左心室舒张功能明显改善。 |
| 关 键 词： | 超声心动图，一氧化氮，肺动脉高压 |
EVALUATION OF THE THERAPEUTIC EFFECT OF NITRIC OXIDE INHALATION ON OBLITERATIVE PULMONARY HYPERTENSION WITH DOPPLER ECHOCARDIOGRAPHY |
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| Affiliation: | (He Jian-Guo, Zhao Yi-Ju ,Cheng Xian-Sheng,et al. (Cardiovascular Institute and FuWai Hospital,CAMS and PUMC,Beijing) |
| Abstract: | To evaluate the therapeutic effect of nitric oxide inhalation on obliterative pulmonary hypertension, fifteen cases of obliterative pulmonary hypertension including eight with primary and seven with thromboembolic pulmonary hypertension were studied with hoppler echocardiography. The results showed that the mean peak pressure gradient across tricuspid valves during systole decreased by 22. 5/00 (p<0. 001 ) after inhalation of nitric oxide indicating reduction of pulmonary hypertension and resistance load of the right ventricle ,the mean end diastolic volume of the left ventricle increased by 12. 6/00(p<0. 05) showing improvement of the diastolic function of the left ventricle. Inhaled nitric oxide is definitely effective for obliterative pulmonary hyperiension. |
| Keywords: | Echocardiography Nitric oxide Pulmonary hypertension |
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