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Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.
Authors:Sven A Lang  Christian Moser  Andreas Gaumann  Dagmar Klein  Gabriel Glockzin  Felix C Popp  Marc H Dahlke  Pompiliu Piso  Hans J Schlitt  Edward K Geissler  Oliver Stoeltzing
Affiliation:Department of Surgery, University of Regensburg Medical Center, Regensburg, Germany.
Abstract:
Keywords:
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