Activated platelets in transient global amnesia and TIA |
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| Authors: | Hirabayashi Hisayuki Shimizu Mie Kohara Saori Shinohara Yukito |
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| Affiliation: | Department of Neurology, Tokai University School of Medicine, Boseidai, Isehara, Kanagawa 259-1193, Japan. hhirabay@is.icc.u-tokai.ac.jp |
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| Abstract: | To assess whether platelets are activated in transient global amnesia (TGA) and TIA, blood samples were analyzed by fluorescence-activated cytoscan using antibodies specific for platelet fibrinogen receptor (PAC1) and P-selectin (CD62P). Samples from TIA contained high levels of CD62P compared with age-matched control subjects, whereas those from TGA did not. The authors suggest that activated platelets are involved in brain ischemia, whereas ischemia appears not to be associated with most TGA. |
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