| 骨密度测定在继发性甲状旁腺素机能亢进症骨病中的应用 |
| |
| 引用本文： | 宁建华 吉留悦男. 骨密度测定在继发性甲状旁腺素机能亢进症骨病中的应用[J]. 湖南医科大学学报, 2000, 25(1): 77-79 |
| |
| 作者姓名： | 宁建华 吉留悦男 |
| |
| 作者单位： | [1]湖南医科大学附属湘雅医院肾内科 [2]日本国鹿儿岛鹿屋市池田病院 |
| |
| 摘 要： | 采用双能Ｘ线骨密度测定法检测１８５例慢性肾衰血透患者的桡骨骨密度,计算其Ｚ值,同时检测其血清甲状旁腺素,碱性磷酸酶和指骨Ｘ照片。结果显示：血透患者骨密度低于正常对照组,并随透析时间延长进一步减低;骨密度与其ＰＴＨ,ＡＬＰ和指骨骨膜下吸收呈负相关;用Ｚ值对继发性甲状旁腺机能离进症骨病作诊断试验,受试者运筹特性央线显示,当Ｚ≤－２．２时,灵敏度为７９．４１％,特异度为７８．１５％《
|
| 关 键 词： | 血液透析 骨密度 甲状旁腺机能亢进 继发性 |
The relationship between bone mineral density and secondary hyperparathyroidism bone disease] |
| |
| J P Ning,M Sun,I Toru,Y Etsuo. The relationship between bone mineral density and secondary hyperparathyroidism bone disease][J]. Bulletin of Hunan Medical University, 2000, 25(1): 77-79 |
| |
| Authors: | J P Ning M Sun I Toru Y Etsuo |
| |
| Affiliation: | Department of Nephrology, Xianya Hospital, Hunan Medical University, Changsha 410008. |
| |
| Abstract: | The bone mineral density (BMD) and Z score in distal 1/3 radius were measured with dual energy X-ray absorptiometry (DEXA) in 185 hemodialysis (HD) patients, meanwhile serum parathyroid hormone (PTH), alkaline phosphatase (ALP) and hand X-rays were detected. Results showed that BMD in HD patients was significantly lower than that in control group(P < 0.05), and decreased with dialysis duration increasing. BMD in HD patients was negatively related with PTH, ALP and rate of subperiosteal erosions. By using Z score to diagnose hyperparathyroidism bone disease, receiver operating characteristic (ROC) curve was worked out. If Z score < or = -2.02, the sensitivity was 79.41% and specificity was 78.15%. In conclusion the measurement of BMD is a useful tool for the detection of hyperparathyroid bone disease. |
| |
| Keywords: | |
| 本文献已被 维普 等数据库收录！ |
|
