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Processing of Affective Speech Prosody is Impaired in Asperger Syndrome |
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| Authors: | Pirjo Korpilahti Eira Jansson-Verkasalo Marja-Leena Mattila Sanna Kuusikko Kalervo Suominen Seppo Rytky David L. Pauls Irma Moilanen |
| Affiliation: | (1) Cognitive Laboratory, Clinical Neurophysiology, Oulu University Hospital, Oulu, Finland;(2) School of Finnish and General Linguistics, University of Turku, Turku, Finland;(3) Department of Finnish, Information Studies and Logopedics, University of Oulu, Oulu, Finland;(4) Department of Psychology, Cognitive Brain Research Unit, University of Helsinki, Helsinki, Finland;(5) Department of Child Psychiatry, Oulu University Hospital, Oulu, Finland;(6) Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA |
| Abstract: | Many people with the diagnosis of Asperger syndrome (AS) show poorly developed skills in understanding emotional messages. The present study addressed discrimination of speech prosody in children with AS at neurophysiological level. Detection of affective prosody was investigated in one-word utterances as indexed by the N1 and the mismatch negativity (MMN) of auditory event-related potentials (ERPs). Data from fourteen boys with AS were compared with those for thirteen typically developed boys. These results suggest atypical neural responses to affective prosody in children with AS and their fathers, especially over the RH, and that this impairment can already be seen at low-level information processes. Our results provide evidence for familial patterns of abnormal auditory brain reactions to prosodic features of speech. |
| Keywords: | Asperger syndrome Auditory perception Affective prosody Familial pattern ERP |
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