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Long-term use of deferiprone significantly enhances left-ventricular ejection function in thalassemia major patients |
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| Authors: | Maggio Aurelio Vitrano Angela Lucania Gaetano Capra Marcello Cuccia Liana Gagliardotto Francesco Pitrolo Lorella Prossomariti Luciano Filosa Aldo Caruso Vincenzo Gerardi Calogera Campisi Saveria Cianciulli Paolo Rizzo Michele D'Ascola Giuseppe Ciancio Angela Di Maggio Rosario Calvaruso Giuseppina Pantalone Gaetano Restivo Rigano Paolo |
| Affiliation: | U.O.C. Ematologia II con Talassemia, Ospedali Riuniti P.O. Cervello Palermo, Palermo, Italy. aurelio.maggio@ospedaliriunitipalermo.it |
| Abstract: | A multicenter randomized open-label long-term sequential deferiprone–deferoxamine (DFP-DFO) versus DFP alone trial (sequential DFP-DFO) performed in patients with thalassemia major (TM) was retrospectively reanalyzed to assess the variation in the left ventricular ejection fraction (LVEF) [1]. |
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