Coinfection of Leptomonas seymouri and Leishmania donovani in Indian leishmaniasis |
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Authors: | Ghosh Susmita Banerjee Priyanka Sarkar Avijit Datta Simanti Chatterjee Mitali |
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Affiliation: | Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, India. |
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Abstract: | Leishmania donovani is considered the causative organism of visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL). Testing of 4/29 DNA samples from VL and PKDL patients as well as 2/7 field isolates showed an aberrant internal transcribed spacer 1 (ITS1) restriction fragment length polymorphism (RFLP) pattern, which upon sequencing strongly matched Leptomonas seymouri, thus confirming its presence in Indian leishmaniasis. |
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