先天畸形致畸因素的交互作用分析

本文采用病例——对照研究方法就我们曾证实的三项危险因素间致先天畸形时的交互作用进行了研究。结果发现,仅用药与患病间具有非常显著的正交互影响(P=0.0179),其余对子间无这类关系。本文认为,孕期患病时应谨慎用药,以减少先天畸形发生率。

INTERACTION BETWEEN TERATOGENIC FACTORS

With the case-control method, we studied the interaction among the illness(IL), medicine-take(MT) and chemical expressure(CE) of mother during gestation as to induce the congenital malformation(CM). Only a significant positive interaction between IL and MT was seen, but not between MT and CE or IL and CE. Therefore,it is useful to reduce the incidence of CM that the pregnant woman couldn't take medicine if she was ill.