108例颌骨成釉细胞瘤临床分析

目的:回顾108例成釉细胞瘤的发病年龄、性别、部位、病理类型、手术方式及预后,探讨其内在联系。方法:108例患者按年龄分为7组,分析各年龄段成釉细胞瘤的发生比例、发病部位、病理类型以及复发率;探讨成釉细胞瘤各病理类型与发病部位及复发率的关系;分析手术方式和复发率的关系。结果:108例患者中,20～39岁占56.48%;男性略多于女性;下颌骨发生比例为81.48%;滤泡型占45.37%、丛状型占62.96%。108例患者平均复发率为32.41%,50岁以上者更高;65例患者刮治术后复发率为43.08%,而43例患者根治术后复发率为16.28%;各病理类型复发率分析,滤泡型为34.69%,丛状型为26.47%,棘皮瘤型和颗粒细胞型各为28.57%。结论:成釉细胞瘤以男性青壮年好发,多见于下颌骨磨牙区、下颌支及下颌角部;滤泡型和丛状型为最常见的病理类型,滤泡型较易复发;与刮治术相比,根治性手术可降低复发率。

Clinical analysis of 108 cases of jaw ameloblastoma

PURPOSE: To review the age of onset, gender, sites, pathologic types, operation methods and prognosis, and explore the internal relations in 108 cases of ameloblastoma. METHODS: The patients were divided into 7 groups according to the age, and then the proportion, primary site, pathologic type, and recurrence rate of ameloblastoma in all groups were analyzed. The relationship among pathologic type, recurrence rate and primary site, as well as the relationship between operation methods and recurrence rate were evaluated. RESULTS: In 108 patients, 61 patients were 20-39 years old (56.48%) with more men than women. 88 patients occurred in the mandible(81.48%). Follicular type accounted for 45.37%, and plexiform type accounted for 62.96%. The average recurrence rate of 108 patients was 32.41%, and recurrence was more often in patients over 50 years old. The postoperative recurrence rate of 65 patients treated by curettage was 43.08%, while it was 16.28% in 43 patients treated by radical correction. The recurrent rate was 34.69% in follicular type, 26.47% in plexiform type, and 28.57% in acanthoma type and granular cell type respectively. CONCLUSIONS: Ameloblastoma usually occurs in young men, more frequently in mandibular molar region, ramus and mandibular angle. Follicular type and plexiform type are the most common pathological types. Follicular type relapses more easily. Compared with curettage, radical surgery can reduce the recurrent rate.