The association of endothelial cell signaling,severity of illness,and organ dysfunction in sepsis |
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Authors: | Nathan I Shapiro Philipp Schuetz Kiichiro Yano Midori Sorasaki Samir M Parikh Alan E Jones Stephen Trzeciak Long Ngo William C Aird |
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Affiliation: | Department of Emergency Medicine, Beth Israel Deaconess Medical Center,1 Deaconess Road CC2-W, Boston, MA 02215, USA. nshapiro@bidmc.harvard.edu |
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Abstract: |
Introduction Previous reports suggest that endothelial activation is an important process in sepsis pathogenesis. We investigated the association between biomarkers of endothelial cell activation and sepsis severity, organ dysfunction sequential organ failure assessment (SOFA) score, and death. |
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