类志贺毗邻单胞菌感染的临床和流行病学特征

为进一步探索类志贺毗邻单胞菌在传染性腹泻和食物中毒中的地位和作用,我们于1984年10月至1985年10月对杭州市中医医院的腹泻病人和部分食物中毒病人进行了本菌的调查。
检测864份腹泻病人和12份食物中毒病人的粪便,发现12株类志贺毗邻单胞菌,阳性率1.37%。此外,还检出痢疾杆菌116株,副溶血性弧菌8株和致病性大肠杆菌2株。本菌感染者的临床症状类似细菌性痢疾的感染。其特征是腹泻呈水样或粘液便,次数较多,个别有里急后重,腹痛明显,1例有绞痛。部分患者有全身症状,如寒战、发热,2例达39℃。全部病例经抗生素和补液治疗,大多在3~5天内症状消失。5例病人病前2天内曾食用小水产品或海水产品,但同一家庭共同食用者未发生腹泻。该菌作为一种新的肠道致病菌,在我市腹泻和食物中毒的病原学中已占有一定地位,应引起关注,并进一步探索了本菌感染的致病机理和防治措施。

A Survey of the Clinical and Epidemio logical Characteristics of Plesiomonas Shigelloides Infection

From Oct, 1984 to Oct, 1985, we have investigated Plesiomonas Shigelloides infection in patients with gastroenteritis and food-poisoning in the Hospital of Chinese traditional Medicine in Hangzhou, in order to explore further the situation and affection of Plesiomonas Shigelloides in diarrhea and food-poisoning.
We examined Stools from 864 patients with diarrhoea and 12 patients with food poisoning and found that 12 strains of Plesiomonas Shigelloides had a prevalence rate of 1.37%. In addition, we isolated simutaneously 16 strains of Shigella, 8 strains of Vibro parahoaemolyticus and 2 strains of enteropathogenic Escherichia coli.
The age of 10 patients was from 15-year-old to 49-year-old, and 9 cases were male while 3 cases were female.
Clinical characteristics of patients infected by Plesiomonas Shigelloides was similar to those affected by Shighlla, an illness characterized by diarrhea with watery or mucous stool and obvious abdominal cramps. A small percentage of patients may have fever, nousea, vomiting and malaise. The median duration of diarrhea is three to four days, None of them Presented severe dehydration. Most of patients being treated with antimicrobial drugs and oral replacement of Salt solution recovered completely after three or five days.
Epidemiologic data suggested that five patients had ingested sea food and raw water within two days before the attack, but other members of their family who had also ingested the same food and water did not develop diarrhoea.
This investigation proves that there were Plesiomonas Shigelloides infection among diarrhoea Patients in Hangzhou. More attention should be payed to this bacterium for further Study chiefly on the pathogenesis of the disease and its preventive measures.