| GLP-1相关降糖药物的临床应用 |
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| 引用本文： | 景国强,李彩萍.GLP-1相关降糖药物的临床应用[J].国际内分泌代谢杂志,2010,30(2). |
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| 作者姓名： | 景国强 李彩萍 |
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| 作者单位： | 内蒙古医学院附属医院内分泌科,呼和浩特,010059 |
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| 摘 要： | 胰高血糖素样肽-1(GLP-1)具备多重抗高血糖作用.近年来基于其治疗2型糖尿病的方案已成为新的研究热点并引起广泛关注.它的几种类似物作为新的降糖药物相继完成Ⅲ期临床研究并在一些国家上市.现就GLP-1的结构、功能,以及几种相关降糖药物的临床研究做一概述.
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| 关 键 词： | 胰高血糖素样肽-1 2型糖尿病 GLP-1类似物 二肽基肽酶-Ⅳ |
Clinical progress of GLP-1 based therapy on diabetes |
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| JING Guo-qiang,LI Cai-ping.Clinical progress of GLP-1 based therapy on diabetes[J].International JOurnal of Endocrinology and Metabolism,2010,30(2). |
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| Authors: | JING Guo-qiang LI Cai-ping |
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| Abstract: | GLP-1 has multiple effect on anti-hyperglycemia,thus the therapy based on GLP-1 in type 2 diabetes mellitus has been extensive reported.Accompanied with the completion of phase Ⅲ study,GLP-1 analogues were lunched in some countries.This review focuses on the structure and functions of GLP-1, and the updated clinical development on the agents based on it. |
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| Keywords: | Glucagon-like peptide-1 Type 2 diabetes mellitus GLP-1 analogues Dipepfidyl-pepti-dase Ⅳ |
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