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脂质代谢与妊娠高血压疾病的研究进展
引用本文:郭海香,高眉扬. 脂质代谢与妊娠高血压疾病的研究进展[J]. 中国妇幼健康研究, 2006, 17(2): 106-108
作者姓名:郭海香  高眉扬
作者单位:广州医学院第二附属医院妇产科,广东,广州,510260
摘    要:
内皮细胞损伤是妊娠期高血压疾病一系列病理生理变化的关键环节,脂代谢与内皮损伤直接相关,因此,推测与脂代谢有关的关键物质脂蛋白脂酶、载脂蛋白E可能在妊娠期高血压疾病中起一定作用.

关 键 词:载脂蛋白E  脂蛋白脂酶  多态性  子痫前期
文章编号:1673-5293(2006)02-0106-03
收稿时间:2005-12-12
修稿时间:2005-12-12

Progress in study on relationship between lipid metabolism and pregnancy-induced hypertension
GUO Hai-xiang,GAO Mei-yang. Progress in study on relationship between lipid metabolism and pregnancy-induced hypertension[J]. Chinese Journal of Maternal and Child Health Research, 2006, 17(2): 106-108
Authors:GUO Hai-xiang  GAO Mei-yang
Affiliation:Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Guangzhou Medical College, Guangdong Guangzhou 510260, China
Abstract:
The endothelial injury is a key step in a series of pathophysiological changes of pregnant women with pregnancy-induced hypertension(PIH),and the abnormal lipid metabolism is closely and directly associated with endothelial injuries.Lipoprotein lipase(LPL) and apolipoprotein E(apoE) are the key substances in lipid metabolism,so we speculated that LPL and apoE may play some roles in development of PIH.
Keywords:apolipoprotein E  lipoprotein lipase  gene polymorphism  preeclampsia  
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