密闭式吸痰管更换频率对吸痰管管壁细菌定植的影响

目的观察24h和72h更换密闭式吸痰管对吸痰管尖端细菌定植的影响，为临床合理制定密闭式吸痰管更换时间提供依据。方法将人选的66例患者使用抽签法随机分为两组：24h组（每24h更换1次密闭式吸痰管）及72h组（每72h更换1次密闭式吸痰管）各33例，其中72h组有6例被剔除，实际为27例，比较两组更换的吸痰管尖端管壁细菌定植率及定植菌密度的差异。结果导管细菌定植总发生率、24h组发生率及72h组发生率分别为65％、61％、70％，组间差异无统计学意义（P〉0．05）。定植菌密度72h组与24h组差异无统计学意义（P〉0．05）。结论本研究显示每24h与每72h更换1次吸痰管对密闭式吸痰管细菌定植的影响差异无统计学意义，提示每72h更换密闭式吸痰管也是安全的，进一步的结论仍需大样本随机对照临床研究来证实。

Influence of Replacement Frequence of Closed Suction Catheter on Bacterial Colonization on the Catheter Wall

Objective To observe the influence of replacements of closed suction systems once every 24 h and every 72 h on bacterial colonization on the closed suction catheter wall. Methods 60 patients undergoing mechanical ventilation were randomized into 24 h group (where the closed suction catheter was replaced once every 24 h,n=33) and 72 h group (where the closed suction catheter was replaced once every 72 h,n=27). The incidence rate of bacterial colonization on the tip of catheter and the density of colonized ba...