递增式血液透析和残余肾功能

残余肾功能是肾脏受损后健存肾单位的滤过、重吸收和内分泌功能,它不仅可以维持水、电解质和酸碱平衡,还可清除小分子、中分子和蛋白结合类毒素,与血液透析患者的预后息息相关.当前,残余肾功能的主要评估方法为尿素氮清除率.对于有残余肾功能的血液透析患者,应该结合残余肾功能水平采用标准尿素清除指数(standard K t/Vur...

Incremental hemodialysis and residual kidney function

Residual kidney function plays critical roles in controlling water,electrolyte and acid-base balance and removing small-molecular-weight toxins in patients with end-stage renal disease.Additionally,residual kidney function also has the ability to remove middle-molecular-weight and protein-binding toxins.Endogenous clearance conferred by residual kidney function is significantly associated with survival.Hemodialysis adequacy of the patients with considerable residual kidney function should be evaluated by stdKt/Vurea.Currently,incremental hemodialysis has been attracted more attention because of its benefit of protecting residual kidney function.With incremental hemodialysis the hemodialysis dose is adjusted according to the level of residual kidney function.It has been reported that incremental hemodialysis can improve the quality of life and anemia management,reduce serumβ2-microglobulin,alleviate economic burden,and even increase survival rate.However,more evidences are required to support this strategy.