| 利用活性部位指纹图谱筛选驱虫斑鸠菊提取工艺 |
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| 引用本文： | 于鲁海,李燕菊,孙力,尚靖,徐建国. 利用活性部位指纹图谱筛选驱虫斑鸠菊提取工艺[J]. 中药材, 2007, 30(12): 1589-1591 |
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| 作者姓名： | 于鲁海 李燕菊 孙力 尚靖 徐建国 |
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| 作者单位： | 新疆维吾尔自治区人民医院临床药学研究所,新疆乌鲁木齐,830001 |
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| 摘 要： | 目的:以活性部位指纹图谱为模板,探讨建立驱虫斑鸠菊提取工艺的可行性。方法:采用正交实验设计,以活性部位的HPLC指纹图谱色谱峰的变化为指标,应用多指标实验公式评分法考察提取工艺条件。结果:驱虫斑鸠菊的最佳提取工艺为,加入10倍量水,浸泡1 h,煎煮1 h,共3次。结论:所选工艺条件具有科学、简单、实用的特点。
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| 关 键 词： | 驱虫斑鸠菊 正交实验 HPLC指纹图谱 多指标实验 公式评分法 提取工艺 |
| 文章编号： | 1001-4454（2007）12-1589-03 |
| 收稿时间： | 2007-04-19 |
| 修稿时间： | 2007-04-19 |
Application of Fingerprint of Active Part on Extraction Techniques for Vernonia anthelmintica |
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| YU Lu-hai,LI Yan-ju,SUN Li,SHANG Jing,XU Jian-guo. Application of Fingerprint of Active Part on Extraction Techniques for Vernonia anthelmintica[J]. Journal of Chinese medicinal materials, 2007, 30(12): 1589-1591 |
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| Authors: | YU Lu-hai LI Yan-ju SUN Li SHANG Jing XU Jian-guo |
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| Affiliation: | The Clinical Medical Institute of Xinjiang, Urunqi 830001, China |
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| Abstract: | Objective:To probe into feasibility of extraction techniques for Vernonia anthelmintica using HPLC fingerprint of active part as model.Methods:The extraction techniques were studied by multi-index test experiment formula evaluation and orthogonal design,which took change of peak area in HPLC fingerprint of active part for Vernonia anthelmintica as indices.Results:The optimum extracting procedure was as follows:using 10 times volume of water for each time,soaking one hour and then boiling for three times sustaining one hour each.Conclusion:It is scientific,simple and applicable. |
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| Keywords: | Vernonia anthelimintica Orthogonal design HPLC fingerprint Multi-index test Experiment formula evaluation Extraction technique |
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