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Vaccines and autoimmunity during the COVID-19 pandemic
Authors:Tsvetelina Velikova
Institution:Tsvetelina Velikova, Department of Clinical Immunology, University Hospital Lozenetz, Sofia 1407, BulgariaTsvetelina Velikova, Medical Faculty, Sofia University, Sofia 1407, Bulgaria
Abstract:To control the pandemic, efficient vaccines must be applied to the population, including patients with autoimmune diseases. Therefore, one can expect that coronavirus disease 2019 (COVID-19) vaccines may influence the underlying autoimmune processes in these patients. Additionally, it is essential to understand whether COVID-19 vaccines would be effective, safe, and provide long-lasting immunological protection and memory. However, the currently available and approved COVID-19 vaccines turned out to be safe, effective, and reliable in patients with autoimmune inflammatory and rheumatic diseases. Furthermore, most patients said they felt safer after getting vaccinations for COVID-19 and reported enhanced overall quality of life and psychological wellbeing. In general, the COVID-19 vaccines have been highly tolerated by autoimmune patients. Such findings might comfort patients who are reluctant to use COVID-19 vaccines and assist doctors in guiding their patients into receiving vaccinations more easily and quickly.
Keywords:SARS-CoV-2  COVID-19  Immune response  COVID-19 vaccine  Immune memory  Autoimmunity  Autoimmune diseases  Relapse
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