| 原发性甲状旁腺功能亢进症诊断及手术治疗进展 |
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| 引用本文： | 崔铭,王鸥,廖泉. 原发性甲状旁腺功能亢进症诊断及手术治疗进展[J]. 协和医学杂志, 2020, 11(4): 395-401. DOI: 10.3969/j.issn.1674-9081.2020.04.007 |
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| 作者姓名： | 崔铭 王鸥 廖泉 |
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| 作者单位： | 1.中国医学科学院 北京协和医学院 北京协和医院 基本外科, 北京 100730 |
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| 基金项目： | 中国医学科学院医学与健康科技创新工程2017-I2M-1-001 |
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| 摘 要： | 原发性甲状旁腺功能亢进症(primary hyperparathyroidism, PHPT)是引起高钙血症的最常见病因, 由一个或多个甲状旁腺病理性过量分泌甲状旁腺激素(parathyroid hormone, PTH)所致。随着血钙及PTH检查的普及, PHPT的发病率明显增加, 成为影响人类健康的常见内分泌疾病, 其诊治理念也在不断更新。绝大多数PHPT为散发性, 约5%~10%的病例以遗传性PHPT的形式发病。本文讨论PHPT的诊断及手术治疗进展, 以期为临床提供借鉴。
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| 关 键 词： | 原发性甲状旁腺功能亢进症 遗传性疾病 诊断 手术治疗 |
| 收稿时间： | 2020-02-10 |
Advances in Diagnosis and Surgical Treatment of Primary Hyperparathyroidism |
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| Affiliation: | 1.Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China2.Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China |
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| Abstract: | Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia, which is due to excessive secretion of parathyroid hormone (PTH) from one or several parathyroid glands. With the tests of serum calcium and PTH being routinely employed, the incidence of PHPT has distinctly increased and PHPT has become a common endocrine disorder. The concept of diagnosis and treatment for PHPT has been developing continuously. Most cases of PHPT are sporadic, while 5%-10% of cases are hereditary. In this literature, we reviewed the advances in diagnosis and surgical treatment of PHPT. |
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