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| 兔颅内血肿吸收速度比较及VWF的表达 | |
| 引用本文： | 陶胜忠,苏芳忠,杨金庆,张云汉,冯广森,刘郑和.兔颅内血肿吸收速度比较及VWF的表达[J].郑州大学学报(医学版),2001,36(6):675-677. |
| 作者姓名： | 陶胜忠 苏芳忠 杨金庆 张云汉 冯广森 刘郑和 |
| 作者单位： | 1. 河南医科大学第二附属医院神经外科, 2. 中原油田总医院神经外科, 3. 河南医科大学病理教研室, 4. 河南医科大学第二附属医院放射科, |
| 摘 要： | 目的 :探讨新生血管对颅内血肿吸收的影响。方法 :家兔 5 4只 ,分为A、B、C、D 4组。B、C、D 3组分别制作硬膜外血肿 (epiduralhematoma ,EDH)、硬膜下血肿 (subduralhematoma ,SDH)及脑内血肿 (intracerebralhematoma ,ICH)实验性家兔颅内血肿动物模型。CT观察各血肿的动态改变 ,同时检测早期不同血肿周围VWF的表达。结果 :3组中以D组ICH吸收最快 ,其血肿周围新生血管数量最多 (P <0 .0 5 )。结论 :颅内血肿形成后 ,其血肿周围新生血管的形成对血肿的自身溶解、吸收具有重要的意义 |
| 关 键 词： | 颅内血肿 CT VWF 兔 |
| 修稿时间： | 2001年7月10日 |
Absorption of intracranial hematoma and expression of VWF in rabbits |
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| TAO Shengzhong ,SU Fangzhong ,YANG Jinqing ,ZHANG Yunhan FENG Guangsen ,LIU Zhenghe.Absorption of intracranial hematoma and expression of VWF in rabbits[J].Journal of Zhengzhou University: Med Sci,2001,36(6):675-677. | |
| Authors: | TAO Shengzhong SU Fangzhong YANG Jinqing ZHANG Yunhan FENG Guangsen LIU Zhenghe |
| Institution: | TAO Shengzhong 1),SU Fangzhong 1),YANG Jinqing 2),ZHANG Yunhan 3) FENG Guangsen 4),LIU Zhenghe 4) 1)Department of Neurosurgery,the Second Affiliated Hospital,Henan Medical University,Zhengzhou 450003 2)Department of Neuro |
| Abstract: | Aim: To explore the influence of newly built vessels on the absorption of intracranial hematoma. Methods: A total of 54 rabbits were divided into 4 groups.Gronp B,C and D were used to build the experiment models of epidural hematoma (EDH), subdural hematoma(SDH) and intracerebral hematoma(ICH) with group A as normal control,and the hematoma absorption was observed by computed tomography, meanwhile, the expression of VWF was detected by immunohistochemical method. Results: The ICP absorption rate of group D was higher than those of group B and C( P< 0.05) when localization and blood volume were the same.The expression of VWF of group D was highest.Conclusion: The newly built vessels around the areas of intracranial hematoma may promote the absorption of hematoma. |
| Keywords: | intracranial hematoma CT VWF rabbit |
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