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COLLABORATIVE STUDY OF THE FREQUENCY OF THE FLUORIDE-RESISTANT CHOLINESTERASE VARIANT IN PATIENTS WITH MALIGNANT HYPERPYREXIA |
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| Authors: | EVANS, R. T. IQBAL, J. ELLIS, F. R. HALSALL, P. J. DIETZ, A. A. LUBRANO, TINA RUBINSTEIN, H. M. |
| Affiliation: | Department of Clinical Biochemistry, St James's University Hospital Leeds LS9 7TF University Department of Anaesthesia, St James's University Hospital Leeds LS9 7TF Research and Medical Services, Veterans Administration Hospital Hines, Illinois 60141, U.S.A. *Present address: Biochemistry Laboratory, West Park Hospital Epsom, Surrey KT19 8PB |
| Abstract: | Cholinesterase phenotyping studies have been carried out intwo laboratories on blood specimens from 28 patients shown tobe susceptible to malignant hyperpyrexia. In contrast to previouslypublished reports, no evidence could be found for an increasein the frequency of the E1uE1f genotype above that known tooccur in the general population. |
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