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木聚糖酶的亚慢性毒性研究
引用本文:程东,韩晓英,鲁传宏,张天亮,姚文环. 木聚糖酶的亚慢性毒性研究[J]. 中国卫生检验杂志, 2007, 17(4): 696-697,753
作者姓名:程东  韩晓英  鲁传宏  张天亮  姚文环
作者单位:1. 山东省疾病预防控制中心,济南,250014
2. 山东师范大学,济南,250014
3. 济南市槐荫区疾病预防控制中心,济南,250022
摘    要:
目的:研究木聚糖酶的亚慢性毒性作用。方法:根据GB15193-2003《食品安全性毒理学评价程序和方法》设104.2、208.4、416.7、833.3mg/kg 4个剂量组,进行大鼠亚慢性毒性试验研究。结果:木聚糖酶大鼠亚慢性毒性试验各剂量组各指标均未显示明显毒性作用。结论:在本次实验条件下,木聚糖酶在833.3mg/kg剂量下未显示有毒性作用。

关 键 词:木聚糖酶  亚慢性毒性试验
文章编号:1004-8685(2007)04-0696-03
收稿时间:2006-10-09
修稿时间:2006-10-09

Subchronic toxicity of xylanase
Cheng Dong,Han Xiao-ying,Lu Chuan-hong,Zhang Tian-liang,Yao Wen-huan. Subchronic toxicity of xylanase[J]. Chinses Journal of Health Laboratory Technology, 2007, 17(4): 696-697,753
Authors:Cheng Dong  Han Xiao-ying  Lu Chuan-hong  Zhang Tian-liang  Yao Wen-huan
Affiliation:1. Shandong Center for Disease Control and Prevention, Jinan 250014, China; 2. Shandong Normal University, Jinan 250012, China; 3. Huaiyin Center for Disease Control and Prevention, Jinan 250022,China
Abstract:
Objective:To investigate the subchronic toxicity of xylanase.Methods:Four dose groups of 104.2,208.4,416.7,833.3 mg/kg were administered to rats in subchronic toxicity test according to GB15193-2003 "Procedures and methods for toxicological assessment of food".Results:The results of the subchronic toxicity test were negative.Conclusion:Xylanase is a substance with no subchronic toxicity under the condition of this study.
Keywords:Xylanase   Subchronic toxicity test
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